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Fig. 3 | Retrovirology

Fig. 3

From: Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

Fig. 3

Single cell differences in HIV target levels. a Violin plots representing spread and variability of HIV target levels (40-cycle threshold). Individual cells are denoted by dots and median levels are indicated by horizontal lines. b Heatmap of cell-to-cell variation in levels of each HIV target (rows). Cells are grouped on the basis of cell line and ordered from high to low level of HIV TAR. Each vertical line represents a single cell. Color scale (below) indicates HIV target levels. c Correlation matrices for levels of each HIV target in latently-infected (U1, ACH-2, J-Lat 9.2; upper panel) and productively-infected (activated J-Lat 9.2 and 8E5; lower panel) cell lines. Nef has been excluded from these analyses. Color scale denotes Spearman coefficients

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