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Fig. 5 | Retrovirology

Fig. 5

From: Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

Fig. 5

Correlation between HIV targets and cellular transcripts. a Correlation matrix showing degree of correlation between expression of each cellular gene (columns) and each HIV target (rows). HIV targets are grouped by cell line. Color scale (right) indicates Spearman r values. b Differential expression of cellular genes between Tat-Rev+ and Tat-Rev− subpopulations of ACH-2, activated J-Lat, and 8E5 cells. Color scale denotes difference in expression level (log2) in Tat-Rev+ cells. P values were calculated using the Wilcoxon rank sum test and corrected for false discovery rate (FDR) using the Benjamini–Hochberg correction; asterisks (*) denote FDR-adjusted P values < 0.05. Dendrograms (above) show unsupervised clustering of cellular factors. Cellular genes for which no expression was detected were excluded from these analyses

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Retrovirology

ISSN: 1742-4690

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