Table 1 Recapitulation of the susceptibility of in vitro and in vivo infection, the capacity for viral transmission and the immune response adopted by the different cell types upon HTLV-1 infection
From: HTLV-1 infection of myeloid cells: from transmission to immune alterations
Cell type/condition | Mucosal DC (TGF-β derived) | MDDC (IL-4 derived) | myDC | pDC | Monocyte | Macrophage | HSC |
|---|---|---|---|---|---|---|---|
In vitro infection | + | + | + | ± | – | ? | ? |
In vivo infection | ? | n/a | + | +* | +* | + | + |
In vitro transmission | ? | + | + | ± | – | ? | ? |
Ex vivo immune response | ? |
| ? |
|
|
| ? |
CD80, CD86,
IFNα