Fig. 2
From: HTLV-1 bZIP factor: the key viral gene for pathogenesis
Functions of HBZ. HBZ induces transcription of Foxp3, CCR4 and TIGIT genes. HBZ expression promotes the proliferation of T cells and inhibits their apoptosis. In addition, HBZ changes expressing T cells to an effector/memory phenotype, which is important for their migration into breast milk and semen