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Fig. 1 | Retrovirology

Fig. 1

From: Transmitted/founder SHIV.D replicates in the brain, causes neuropathogenesis, and persists on combination antiretroviral therapy in rhesus macaques

Fig. 1

Quantitative immunohistochemistry of immune cell markers in TF SHIV.D RM brain tissue. Immunohistochemistry (IHC) staining of CD68+, MAC387+, and CD3 + cells in brain tissue of progression, off-ART, and ART suppressed RMs (A). Representative images from occipital, temporal, and frontal lobes at 10X magnification are shown. Scale bar = 200 μm. Target cells were quantified using Keyence BZ-X700 Microscope and accompanying Batch Analysis Software to determine the average number of IHC stained cells from 10 nonoverlapping 20X images per brain section of each RM (B). 20X frame area = 393,880 μm². Box and whisker plots are presented as mean values of counts ± quartiles, with whiskers representing the range

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Retrovirology

ISSN: 1742-4690

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