Fig. 5

STRING protein network map of HIV-1 Gag interacting host chromatin proteins. Protein lists were generated from mass spectrometry experiments of Gag interacting proteins. Gene lists were then categorized into gene ontology (GO) terms to identify those which were chromatin associated. This refined list was input into STRING Consortium v12.0 (https://string-db.org/) to generate a protein–protein interaction map. A total of 129 proteins were queried and the following physical protein–protein interactions were made. Among the 129 proteins queried, 117 proteins are displayed after a minimum required interaction score of 0.4 was applied. Proteins that do not have any interacting partners are shown at the bottom left corner of the map. Lines are generated based on known interactions (purple lines), predicted gene fusions (red lines), predicted gene neighborhoods (green lines), and predicted gene co-occurrences (blue lines) from the literature