Fig. 5

HTLV-1c tax is present at significantly higher levels than gag in PBMCs and T-cells. A Schematic of HTLV-1 provirus genome and positions of gag and tax primers and probes for ddPCR amplification. B Distributions of proviral load (PVL), HTLV-1c copies per 10⁶ PBMCs and per 10⁶ T-cells, detected by ddPCR targeting gag (green dots) and tax (blue hollow circles) gene regions, of 22 HTLV-1c positive subjects from Alice Springs Hospital cohort in Central Australia. Each data point represents a participant, and data shown for each participant are the mean values of quadruplet measurements. Median with interquartile range is shown by black lines. Statistical significance between matching data was assessed using Wilcoxon matched-pairs signed rank test (p, 0.0005, 0.0009, respectively)