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Table 1 Demographics and clinical characteristics of participants from Central Australia according to HTLV-1c status

From: High level of genomic divergence in orf-I p12 and hbz genes of HTLV-1 subtype-C in Central Australia

 

HTLV-1c–

(n = 15)

HTLV-1c + 

(n = 22)

p-value

Demographics, n (%)

 Median age

40.0

49.5

0.15

 Female at birth

7/15 (46.7%)

13/22 (59.1%)

0.52

 Male at birth

8/15 (53.3%)

9/22(40.1%)

Lifestyle, n (%)

 Smoker (current or previous)

8/15 (53.3%)

9/15 (60.0%)Ø

 > 0.99

 Harmful alcohol consumption

9/15 (60.0%)

9/17 (52.9%)Ø

0.73

Comorbidities, n (%)

 Asthma

2/15 (13.3%)

2/22 (9.1%)

 > 0.99

 Ischaemic heart disease

2/15 (13.3%)

4/22 (18.2%)

 > 0.99

 Diabetes

6/15 (40.0%)

11/22 (50%)

0.72

 Chronic liver disease (CLD)

0/15 (0%)

3/22 (13.6%)

0.26

 Chronic kidney disease (CKD)

7/15 (46.7%)

13/22 (59.1%)

0.52

 Hepatitis B Virus (HbsAg)

0/9 (0%)Ø

2/20 (10.0%)Ø

 > 0.99

Potential HTLV-1 associated diseases, n (%)

 Pulmonary Disease

5/15 (33.3%)

9/22 (40.1%)

0.74

 Strongyloidiasis, current

2/15 (13.3%)

2/21 (9.5%)Ø

 > 0.99

 Blood stream infection (BSI)

0/15 (0%)

10/22 (45.5%)

0.002**

 HTLV-1 associated myelopathy (HAM)

0/15 (0%)

0/22 (0%)

 > 0.99

 Adult T cell leukemia/lymphoma (ATL)

0/15 (0%)

0/22 (0%)

 > 0.99

  1. ** Bold indicates high statistical significance, p ≼ 0.01
  2. HbsAg, HBV surface antigen
  3. BSI includes current or previous infection
  4. Pulmonary disease includes chronic obstructive pulmonary disease (COPD), chronic suppurative lung disease (CSLD), bronchiectasis and bronchiolitis
  5. Missing data are indicated with Ø
  6. Statistical significance assessed using Mann–Whitney test for continuous variables and Fisher’s exact test for categorical variables