Fig. 2

Identification of DE-EVE families using gene set enrichment analysis (GSEA). (a) GSEA bar plot of 1,517 DE-EVE ORFs, annotated using the GMT-formatted annotation file of Repbase-EVE families. (b) Common DE-EVE families and common core enriched DE-EVE ORFs in two analyzed datasets described in a. (c) Expression profile heatmap of 14 extracted DE-EVE families in AML cells from TCGA-LAML. (d) Expression value (transcripts per million; TPM) of DE-EVE families in AML cells from TCGA-LAML (red) and HPCs in GSE111085 (blue). Bars indicate the median